An optimization strategy for structure-activity studies

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dc.contributor.advisorDeming, Stanley N.
dc.contributor.committeeMemberKadish, Karl M.
dc.contributor.committeeMemberCox, James R., Jr.
dc.contributor.committeeMemberParker, George R.
dc.creatorIm, Hyunsook
dc.date.accessioned2022-02-21T14:43:13Z
dc.date.available2022-02-21T14:43:13Z
dc.date.issued1977
dc.description.abstractThe design and synthesis of optimally effective drugs is normally a slow and tedious process. Recent literature evaluations of the functional relationships between structural parameters and biological activity suggest a new strategy of optimization in structure - activity studies. It is shown that this new strategy is effective for several aromatic compounds, and only five compounds might need to be synthesized before an optimally effective drug can be obtained.
dc.description.departmentChemistry, Department of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other3826780
dc.identifier.urihttps://hdl.handle.net/10657/8836
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleAn optimization strategy for structure-activity studies
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Natural Sciences and Mathematics
thesis.degree.departmentChemistry, Department of
thesis.degree.disciplineChemistry
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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