Alterations in chicken cerebrospinal fluid proteins by metabolic manipulation

dc.contributor.advisorHazelwood, Robert L.
dc.contributor.committeeMemberBartel, Allen H.
dc.contributor.committeeMemberLawrence, Addison Lee
dc.contributor.committeeMemberMailman, David S.
dc.creatorBaker, Linda Ann
dc.description.abstractBefore initiating a thorough investigation of proteinaceous components of chicken cerebrospinal fluid (CSF) and possible hormone-barrier characteristics, it was thought desirable to gather preliminary data on normal plasma and CSF protein components by use of a polyacrylamide disc gel electrophoretic (PAGE) technique in addition to standard biochemical analyses. Fasting, Tolbutamide injection, and pancreatectomy were employed to alter plasma parameters and to witness alterations, if any, in CSF which occurred tandem to those observed in plasma. Fasting for periods up to 72 hours caused mainly a decrease in immunoglobulin (G and M), minor transferrin and ultimately major transferrin levels. Virtually all the electrophoretic bands in CSF samples were decreased during the first 48 hours of starvation, although at 72 hours albumin, major transferrin and IgM levels increased. Fasting was without significant impact on plasma or CSF glucose levels; neither did the starvation period alter plasma or CSF insulin levels. [...]
dc.description.departmentBiology and Biochemistry, Department of
dc.format.digitalOriginreformatted digital
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. Section 107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleAlterations in chicken cerebrospinal fluid proteins by metabolic manipulation
dc.type.genreThesis of Natural Sciences and Mathematics, Department of of Houston of Science


Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
1.98 MB
Adobe Portable Document Format