Interaction between Liver X Receptor Beta and Estrogen Receptor Alpha Variants in vitro

Simple item page
dc.contributorUmetani, Michihisa
dc.contributor.authorLe, Rosemarie
dc.contributor.authorWu, Jacky
dc.contributor.authorRezaei, Hengameh
dc.contributor.authorAsghari, Arvand
dc.date.accessioned2021-02-23T16:22:39Z
dc.date.available2021-02-23T16:22:39Z
dc.date.issued2019
dc.description.abstractThis project tests the interaction between the protein Liver X Receptor beta (LXR-beta) and variants of Estrogen Receptor alpha (ER-alpha) proteins in the presence of different ligands. The plasmids were modified in the lab and proteins were made from these plasmids using the coupled transcription/translation system. The techniques used were Co-Immunoprecipitation and Western Blot. The result shows interesting and unexpected interactions between LXR-beta and ER-alpha variants. More study is needed to measure the specific affinity of LXR-beta to each ER-alpha variant and the effect of these complexes.
dc.description.departmentBiology and Biochemistry, Department of
dc.description.departmentHonors College
dc.identifier.urihttps://hdl.handle.net/10657/7536
dc.language.isoen_US
dc.relation.ispartofSummer Undergraduate Research Fellowship
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.titleInteraction between Liver X Receptor Beta and Estrogen Receptor Alpha Variants in vitro
dc.typePoster

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Le_Rosemarie_URD2019.pdf
Size:
693.98 KB
Format:
Adobe Portable Document Format
Download

Collections

Undergraduate Research Day Student Projects