Synthesis of organophosphorous hydrazides and structurally related compounds

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dc.contributor.advisorCates, L. A.
dc.contributor.committeeMemberDriever, Carl W.
dc.contributor.committeeMemberZlatkis, Albert
dc.creatorSachanandani, Suresh B.
dc.date.accessioned2022-06-20T16:07:38Z
dc.date.available2022-06-20T16:07:38Z
dc.date.issued1974
dc.description.abstractQuarternary ammonium compounds generally possess anticholinergic activity. An example of this is the ganglionic Mocking agent, hexa-methonium chloride: (CHg)g-N+-(CH[subscript 2])[subscript 6]-N+-(CH[subscript 3])[subscript 3] 2 Cl -. Procarbzine, which has the structure: (p-CH[subscript 2]-NH-NH-CH[subscript 3]PhCONHCH(CH[subscript 3])[subscript 2] is an antineoplastic agent. The hydrazine moiety in this compound appears with frequency in antineoplastic agents. Keeping these structure-activity relationships in mind, the following compounds were synthesized for biological evaluation.[...]
dc.description.departmentPharmacy, College of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other2182966
dc.identifier.urihttps://hdl.handle.net/10657/9415
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. Section 107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleSynthesis of organophosphorous hydrazides and structurally related compounds
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Pharmacy
thesis.degree.departmentPharmacy, College of
thesis.degree.disciplinePharmacy
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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