Effects of Mesenchymal Stem Cells (MSCs) on Cancer Cell Proliferation and Apoptosis
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Abstract
Mesenchymal stem cells (MSCs), also known as medicinal signaling cells are known for being multi-potent. They are among the most frequently used cell types for regenerative medicine and can be found in every organ and exhibit multilineage differentiation into cell type. Due to their anticancer properties, MSCs have attracted interest in the development of anticancer therapies. Many studies have shown the beneficial effects of MSC-based therapies and its therapeutic potential in radiation oncology is a growing domain of cell therapy. Interestingly, it has also been found that MSCs can serve as vehicles for delivering targeted therapy to tumors and metastatic diseases due to their tumor-trophic properties. This study aims to further elucidate the effects of MSCs on tumor suppression and its potential in stem cell therapy.