Characterization of an agar component which influences antibiotic activity

Simple item page
dc.contributor.advisorBennett, E. O.
dc.contributor.committeeMemberEvans, John E.
dc.creatorHanus, Frank Joseph
dc.date.accessioned2022-02-08T21:11:18Z
dc.date.available2022-02-08T21:11:18Z
dc.date.issued1966
dc.description.abstractBacto agar reversed the effect of basic antibiotics while acidic and amphoteric antibiotic were not markedly affected. The reversal of activity was shown to be due to the presence of a diffusable, non-dialyzable sulfated polyanionic carbohydrate. This substance was shown to bind cationic dyes and form insoluble complexes with some basic antibiotics. Antibiotic activity was not markedly affected by the pore size of the agar or by the presence of diffusable, physiologically active substances in the agar. Such of the antagonism of Bacto agar was removed by precipitation of the agar with ethanol or by extraction of polymerized agar with ammonium hydroxide. It is possible that the ammonium hydroxide extraction may be commercially feasible and will yield an agar product suitable for the evaluation of antibiotic activity.
dc.description.departmentBiology and Biochemistry, Department of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other17972051
dc.identifier.urihttps://hdl.handle.net/10657/8673
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleCharacterization of an agar component which influences antibiotic activity
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Arts and Sciences
thesis.degree.departmentBiology, Department of
thesis.degree.disciplineBiology
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hanus_1966_17972051.pdf
Size:
4.11 MB
Format:
Adobe Portable Document Format
Download

Collections

Legacy Theses and Dissertations (1940-2009)