The effects of glucose, glucagon and sulfonylureas on insulin release from chicken pancreatic pieces

dc.contributor.advisorHazelwood, Robert L.
dc.contributor.committeeMemberBartel, Allen H.
dc.contributor.committeeMemberLawrence, Addison Lee
dc.contributor.committeeMemberMailman, David S.
dc.contributor.committeeMemberFarmer, R. W.
dc.creatorNaber, Stephen Pope
dc.description.abstractInvestigations of insulin release from the avian endocrine pancreas in vivo have indicated some anomalous, if not contradictory, responses to experimental manipulation when compared to similar studies conducted in mammals. In the present work insulin release from the chicken pancreas was studied in vitro in order to evaluate this process without the influence of compensatory homeostatic factors. These investigations were conducted by incubating small (20 5mg) pancreatic pieces from Single-Comb, White Leghorn hens in four successive 15-min experimental periods following a 30-min preincubation period. Release of immunoreactive insulin into the incubation medium was measured in response to various glucose concentrations, glucagon, sulfonylureas, and in the presence and absence of extracellular calcium. [...]
dc.description.departmentBiology and Biochemistry, Department of
dc.format.digitalOriginreformatted digital
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleThe effects of glucose, glucagon and sulfonylureas on insulin release from chicken pancreatic pieces
dc.type.genreThesis of Natural Sciences and Mathematics, Department of of Houston of Philosophy


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