A stereoselective total synthesis of antibiotic ([plus-minus])-LL-Z 1271 [proportional to]

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dc.contributor.advisorWelch, Steven C.
dc.contributor.committeeMemberOró, John F.
dc.creatorFleming, William Philip
dc.date.accessioned2022-02-09T17:20:01Z
dc.date.available2022-02-09T17:20:01Z
dc.date.issued1974
dc.description.abstractThe stereoselective total synthesis of (plus-minus)-LL-Z 1271[proportional to] (1) is presented. The general synthetic scheme is shown below. The synthetic approach presented incorporates a new stereo-selective reductive alkylation reaction, a new method of lactonization, and a novel methanolysis reaction to give the title compound (1) and its anomer (2) in a favorable ratio.
dc.description.departmentChemistry, Department of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other13695160
dc.identifier.urihttps://hdl.handle.net/10657/8708
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleA stereoselective total synthesis of antibiotic ([plus-minus])-LL-Z 1271 [proportional to]
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Natural Sciences and Mathematics
thesis.degree.departmentChemistry, Department of
thesis.degree.disciplineChemistry
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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