Investigation on Conducting Polymers-Doped with Laminin

Conducting polymers (CPs) have been used in biomedical science and engineering research field with wide applications such as biosensors/ actuators, drug delivery systems, and implantable devices. Some biocompatible CPs like PEDOT and PPy and their nanostructures have been designed to make devices and further functionalized with biomolecules to increase the attachment and viability of cells. In this thesis, EDOT monomers have been doped with laminin peptides to generate biomolecule doped PEDOT films by electropolymerization experiment. Furthermore, EDOT/ laminin peptide CP films were then coated on PLLA polymer microfibers template to form PEDOT/ laminin nanotubes. The laminin doped PEDOT nanotubes will be tested with experiments of cell attachment and neurite outgrowth in future research.