Factor Structure of the Geriatric Depression Scale and its Relationship to Cognition in Alzheimer's Disease

dc.contributor.advisorMassman, Paul J.
dc.contributor.committeeMemberHiscock, Merrill
dc.contributor.committeeMemberDulay, Mario F., Jr.
dc.creatorHavins, Whitney
dc.date.accessioned2012-04-19T13:18:02Z
dc.date.accessioned2012-04-19T13:18:03Z
dc.date.available2012-04-19T13:18:02Z
dc.date.available2012-04-19T13:18:03Z
dc.date.createdDecember 2011
dc.date.issued2011-12
dc.date.updated2012-04-19T13:18:03Z
dc.description.abstractEvidence suggests that patients with Alzheimer’s disease (AD) experience more frequent and severe apathy and depression than their healthy age counterparts. Moreover, some studies have shown that apathy and depression are associated with greater cognitive and functional decline in these patients. Previous research has shown the Geriatric Depression Scale to be capable of identifying symptoms of both apathy and dysphoria in older adults. However, no study to date has systematically explored whether the Geriatric Depression Scale measures symptoms of apathy and dysphoria in patients with AD and related these constructs to performance on neuropsychological measures. This study employed exploratory factor analysis to identify factors of the Geriatric Depression Scale in a sample of 569 patients with pure probable AD. A four-factor solution was obtained, yielding factors associated with apathy, dysphoria, social withdrawal, and cognitive impairment. It was hypothesized that symptoms of apathy would be associated with cognitive and functional impairment, even after controlling for dysphoria. Two-way ANOVAs showed that endorsement of Apathy factor items was associated with greater impairment in verbal memory and motor speed, as well as functional impairment. Dysphoria was not associated with any cognitive or functional variables. Findings suggest that the GDS may be used as a screening measure for symptoms of apathy in AD, hopefully aiding early identification and intervention to reduce patient and caregiver burden.
dc.description.departmentPsychology, Department of
dc.format.digitalOriginborn digital
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10657/222
dc.language.isoeng
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.subjectGeriatric Depression Scale
dc.subjectAlzheimer's Disease
dc.subjectExploratory factor analysis
dc.subjectApathy
dc.titleFactor Structure of the Geriatric Depression Scale and its Relationship to Cognition in Alzheimer's Disease
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Liberal Arts and Social Sciences
thesis.degree.departmentPsychology, Department of
thesis.degree.disciplinePsychology
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.majorClinical
thesis.degree.nameMaster of Arts

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