Laminin Microdroplet Deposition on Conducting Polymer Films for Neural Regeneration

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dc.contributor.advisorAbidian, Mohammad Reza
dc.contributor.committeeMemberMajd, Sheereen
dc.contributor.committeeMemberWu, Tianfu
dc.creatorSharma, Kartik
dc.date.accessioned2020-01-04T02:15:31Z
dc.date.createdMay 2019
dc.date.issued2019-05
dc.date.submittedMay 2019
dc.date.updated2020-01-04T02:15:31Z
dc.description.abstractConducting polymers are valuable tools in tissue engineering as they can play an important role in enhancing cellular response to guidance cues due to their electrical conductivity. Extracellular matrix proteins like laminin can provide a strong guidance cue to direct cellular regrowth. When combined, these two can prove to be unbeatable alternative for tissue regeneration applications. However, the biggest challenge lies in depositing these proteins on the surface of conducting polymer to get the best response out of neurons for neural regeneration. In this study, various parameters have been optimized to idealize the deposition of laminin on conducting polymer’s surface. From this study, an optimized patterning technique can be established to deposit laminin on PEDOT substrates such that minimum volume of laminin is used, the pattern has very well-balanced distances between adjacent rows and columns, and there is least possible void space between the droplets both in horizontal and vertical directions.
dc.description.departmentBiomedical Engineering, Department of
dc.format.digitalOriginborn digital
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/10657/5743
dc.language.isoeng
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.subjectLaminin
dc.subjectConducting polymers
dc.subjectNeural regeneration
dc.subjectNeurosciences
dc.titleLaminin Microdroplet Deposition on Conducting Polymer Films for Neural Regeneration
dc.type.dcmiText
dc.type.genreThesis
local.embargo.lift2021-05-01
local.embargo.terms2021-05-01
thesis.degree.collegeCullen College of Engineering
thesis.degree.departmentBiomedical Engineering, Department of
thesis.degree.disciplineBiomedical Engineering
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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