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dc.contributor.advisorFletcher, Jack M.
dc.creatorHampton, Lyla 1983-
dc.date.accessioned2014-12-19T14:42:47Z
dc.date.available2014-12-19T14:42:47Z
dc.date.createdMay 2013
dc.date.issued2013-05
dc.identifier.urihttp://hdl.handle.net/10657/844
dc.description.abstractThe present study focused on bilateral variation in the structure (single, duplicated) and size (left or right asymmetry) of the Heschl’s gyrus (HG) in individuals with spina bifida meningomyelocele (SBM). A higher rate of anomalous HG was predicted in the SBM population, particularly in individuals with SBM that presented with atypical handedness and greater frequency of clinical and neural markers. The anomalous HG presentation was predicted to relate to lower verbal and reading performance as well as either a reduced or absent right ear advantage on a dichotic listening task. Children and adults were recruited from an existing cohort, along with typically developing (TD) participants. All participants completed both an MR imaging protocol and a battery of cognitive tests including: verbal and spatial intelligence, reading and math achievement, and monotic and dichotic listening. The structure status of the participants’ HG (single, duplicated) was determined through qualitative coding of MRI scans, and asymmetry of the HG was determined through automated quantification of the HG volume. The results did not indicate a higher rate of anomalous HG (duplicated, right HG asymmetry) in individuals with SBM, and the rate of anomalous HG was also not associated with left hand preference, or with more severe clinical and neural pathology. There was evidence that having anomalous HG led to slightly higher verbal and reading scores in the SBM group. These effects, however, were small compared to the larger influences of socioeconomic status and SBM. Although participants’ group status (TD, SBM) and age influences ear advantage on the dichotic listening task, there was no effect of anomalous HG status. The results suggest that the development of an anomalous HG is separate from the common congenital maldevelopment that occurs in SBM, and the presence of an anomalous HG may contribute to higher verbal and reading performances in this clinical population.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.subjectHeschl's Gyrus
dc.subjectImaging
dc.subjectSpina Bifida
dc.subject.lcshClinical psychology
dc.titleTHE RELATION OF ANOMALOUS HESCHL’S GYRUS AND COGNITIVE PERFORMANCE IN SPINA BIFIDA
dc.date.updated2014-12-19T14:42:47Z
dc.type.genreThesis
thesis.degree.nameDoctor of Philosophy
thesis.degree.levelDoctoral
thesis.degree.disciplinePsychology, Clinical
thesis.degree.grantorUniversity of Houston
thesis.degree.departmentPsychology
dc.contributor.committeeMemberHannay, H. Julia
dc.contributor.committeeMemberLeasure, J. Leigh
dc.contributor.committeeMemberJuranek, Jenifer
dc.type.dcmiText
dc.format.digitalOriginborn digital
dc.description.departmentPsychology
thesis.degree.collegeCollege of Liberal Arts and Social Sciences


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