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dc.contributor.advisorGarey, Kevin W.
dc.contributor.advisorFernandez, Julianna M.
dc.creatorBirney, Patrick J
dc.date.accessioned2018-03-01T17:52:33Z
dc.date.available2018-03-01T17:52:33Z
dc.date.created2014-05
dc.date.issuedMay 2014
dc.date.submittedMay 2014
dc.identifier.urihttp://hdl.handle.net/10657/2631
dc.description.abstractBackground: The 2012 update of the Surviving Sepsis Campaign’s Guidelines for Management of Severe Sepsis and Septic Shock recommends administration of effective antibiotics within the first hour of disease recognition; however literature describing an effective approach to expedite antibiotic administration is sparse. Objective: To determine the effectiveness of a multidisciplinary intervention on reducing antibiotic turnaround time. Methods: A three-arm cohort design was used to assess the impact of the intervention on antibiotic turnaround time. The study consisted of a historical Control taking place in April 2013, Cohort 1 in March 2014 evaluating changes in workflow, and Cohort 2 in April 2014 evaluating activation of a medical logic module (MLM). Results: Workflow revisions reduced turnaround time for stat orders on acute care units by decreasing the percent of orders delayed greater than 4 hours (19.6 vs. 8.4%, p = 0.009), but did not have any effect on any other subpopulation. Activation of the MLM resulted in a 54% decrease in mean turnaround time Cohort 2. Conclusion: The combined effect of the workflow revisions and activation of MLM improved mean antibiotic turnaround time and the percent of first-doses administered within 60 minutes.
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.subjectantibiotics
dc.subjectsepsis
dc.subjectseptic shock
dc.subjectmedical logic module
dc.subjectclinical decision support
dc.subjectMLM
dc.subjectCDS
dc.subjectpharmacy
dc.titleReducing Turn-Around Time for First-Dose Antibiotics
dc.date.updated2018-03-01T17:52:33Z
dc.type.genreThesis
thesis.degree.namePharmacy Administration (MS)
thesis.degree.levelMasters
thesis.degree.disciplinePharmacy Administration
thesis.degree.grantorUniversity of Houston
thesis.degree.departmentPharmacological and Pharmaceutical Sciences, Department of
dc.contributor.committeeMemberHalfon, Rebeca
dc.contributor.committeeMemberVarkey, Alex C.
dc.contributor.committeeMemberMasud, Faisal N.
dc.contributor.committeeMemberHai, Shaikh A.
dc.type.dcmiText
dc.format.digitalOriginborn digital
dc.description.departmentPharmacological and Pharmaceutical Sciences, Department of
thesis.degree.collegeCollege of Pharmacy


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