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dc.contributorCheung, Margaret S.
dc.contributor.authorDaugherty, Caleb M.
dc.contributor.authorGasic, Andrei G.
dc.date.accessioned2018-02-27T15:51:46Z
dc.date.available2018-02-27T15:51:46Z
dc.date.issued2017
dc.identifier.urihttp://hdl.handle.net/10657/2459
dc.description.abstractExperiments on the folding mechanics of Phosphoglycerate Kinase(PGK) confirm a two state thermal transition between the native and denatured states, and a multi-state transition under pressure denaturation. -The introduction of crowding agents reduces the intermediate states under pressure denaturation. -Classical folding theory is based on in vitro experimentation, but does not accurately predict folding mechanics in the crowded cellular environment. -Understanding the in vivo folding process may lead to better treatments for disease associated with protein misfolding.
dc.language.isoen_US
dc.titleInvestigation of the Effect of Crowding on Cooperativity in the Folding of Phosphoglycerate Kinase
dc.typePoster
dc.description.departmentPhysics
dc.description.departmentHonors College


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