Now showing items 21-30 of 30

    • Reduction of Cholesterol in Humanized Mice Using CRISPR/CAS9 

      Bidegain, Sebastian (2017)
      Humanized Mouse. We conduct our experiments on a mouse model that has its hepatocytes (liver cells) repopulated with human cells. This allows us to test our gene editing in human cells, in-vivo. Goal. Our goal is to lower ...
    • Response of Astrocytes to Pressure 

      Singh, Devanshi; Shah, Vrutant; Ulrich, Christina (2017)
      Astrocytes are the most abundant cell type in mammalian brain; however their function in the response to brain injury are poorly understood. Reactive astrocytes mediate the response to neural injury in two waves; initially ...
    • Resuscitation Promoting Factor from Micrococcus luteus 

      Nielsen, Carolyn; Rangel, Jonathan; Bodunrin, Abiodun (2017)
      Many bacteria become dormant when nutrient deprived or in response to environmental stress. Mycobacterium tuberculosis (TB) becomes dormant when challenged by stress or antibiotics, which leads to antibiotic resistance. ...
    • Retention of the Nix/BNIP3 Mitophagic Complex Within ER and Autophagosomes 

      Zamil, Dina; Goli, Karthik (2017)
      Mitophagy involves specific degradation of mitochondria and is vital to cellular health. Ineffective mitophagy is linked to Parkinson’s disease, and damaged mitochondria can lead to inflammation, aging, and programmed cell ...
    • Spatial Distribution in Two Species of Galapagos Damselfish 

      Butler, Nicholas; Durham, Sarah; Sanchez, Rachel (2017)
      In this study we focus on interactions and spatial distributions of two herbivorous fishes, the yellowtail damselfish (Stegastes arcifrons) and the Galapagos ringtail damselfish (Stegastes beebei) and the herbivorous pencil ...
    • State Dependent Effects of Transcranial Rotating Permanent Magnet Stimulation of the Primary Motor Cortex 

      Patel, Chintal P.; John, Blessy S. (2017)
      Non-invasive devices that stimulate the brain can enhance or suppress neuronal activity depending on the frequency, rate, and duration of stimuli. These devices can be useful in brain research, and may help diagnose and ...
    • Targeted Inhibition of Fibroblast Activation 

      Kulkarni, Kartik (2017)
      Cardiovascular disease continues to be one of the leading causes of death in the modern world. Due to the limited regeneration capacity of the mammalian heart, very few options exist to help restore cardiac function post ...
    • The effect of the chromosomal location of the male-determiner on mating success in house fly 

      Hassan, Oluwatomi; Trinh, Tammie; Sriskantharajah, Vyshnika; Oderhowho, Alexander; Torres Gonzalez, Jose; Adhikari, Kiran (2017)
      Sex determination is the molecular process that leads to the development of either a male or a female. Some species are polymorphic for how sex is determined. We do not have a good understanding of why this variation in ...
    • The Search for Allosteric Inhibitors for Rho Associated Kinases 

      Gula, Andrew (2017)
      Rho Kinases or ROCKs are multifunctional kinases involved in cell migration, neurite outgrowth, and smooth-muscle migration. ROCK I and ROCK II have been identified as ROCK isoforms. These isoforms share 92% identity in ...
    • Verification of Chromosomal Inversions along the tgrB1-C1 loci in Dictyostelium discoideum 

      Farahvashi, Patrick (2017)
      Chromosomal inversions readily occur in nature, but their effects have not been thoroughly studied. Dictyostelium discoideum is a social amoeba, that when depleted of food, aggregate into multicellular fruiting bodies ...