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Role of Vascular Oxidative Stress in Hypertension
Hypertension affects 1 in 3 adult Americans and is a primary risk factor for cardiovascular diseases. Better understanding of hypertension pathogenesis is important for development of effective therapeutic agents. An ...
OXIDATIVE STRESS AND RENAL AT1R FUNCTION DURING HYPERTENSION
Angiotensin (Ang) II via renal Ang II type 1 receptors (AT1R) modulates proximal tubular Na/K-ATPase such that, low concentrations of Ang II stimulates Na/K-ATPase whereas at high concentrations the stimulatory effect is ...