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A MICROFLUIDICS APPROACH TOWARDS THE INVESTIGATION OF FREE HEME EFFECTS ON SICKLE CELL HEMOGLOBIN POLYMERIZATION
(2012-05)
Sickle cell hemoglobin (HbS) polymerization is considered to be the primary pathogenic event in sickle cell anemia. In this work we aim at fabricating an integrated microfluidic device with a localized microheater for the ...