Cates, L. A.2022-06-202022-06-2019742182966https://hdl.handle.net/10657/9415Quarternary ammonium compounds generally possess anticholinergic activity. An example of this is the ganglionic Mocking agent, hexa-methonium chloride: (CHg)g-N+-(CH[subscript 2])[subscript 6]-N+-(CH[subscript 3])[subscript 3] 2 Cl -. Procarbzine, which has the structure: (p-CH[subscript 2]-NH-NH-CH[subscript 3]PhCONHCH(CH[subscript 3])[subscript 2] is an antineoplastic agent. The hydrazine moiety in this compound appears with frequency in antineoplastic agents. Keeping these structure-activity relationships in mind, the following compounds were synthesized for biological evaluation.[...]application/pdfenThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. Section 107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.Thesisreformatted digital