Willcott, M. R.2022-02-212022-02-2119773828822https://hdl.handle.net/10657/8857Optimization for 2,6-dichlorocamphane from continuous flow reactions of chlorine with [proportional to]-pinene was accomplished using the simplex algorithm of Spendley, Hext, and Himsworth, as modified by Nelder and Mead. The yields (20-25%) obtained were 3.5 times greater than the best value previously reported in the literature. A central composite design study revealed that a second-order polynomial was not a good approximation for the response surface in carbon tetrachloride. The mole ratio of chlorine to [proportional to]-pinene appeared to have some impact on determining the yield of 2,6-dichlorocamphane, especially when the ratio was less than or approximately equal to one.application/pdfenThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.Thesisreformatted digital