Reitzel, Lorraine R.Linares Abrego, Paulina2019-01-032019-01-032018-10-18http://hdl.handle.net/10657/3903The purpose of this research is to better understand how electronic cigarette (e-cig) dose and flavor impact e-cig use and acceptability if the amount of tobacco in cigarettes were reduced to a non-reinforcing level, which the FDA is considering. This pilot project evaluated the impact of e-cig dose, flavor, and cigarette flavor preference on study e-cig use and satisfaction among cigarette smokers. Participants (n=20) were given study cigarettes with a very low dose of nicotine (0.4 mg/ml) and an E-Cig of either high (36 mg/ml) or low (8 mg/ml) nicotine dose in tobacco, menthol, fruit, and cream flavor to use at home. A within-subjects design was used to expose each participant to the low- and high-dose E-Cig for 3 weeks, each in a counterbalanced fashion. Because of the small number of participants, we did not conduct statistical analyses, but instead report means and frequencies. These preliminary results indicated that the lower dose e-cigs were preferred to the higher dose e-cigs, and menthol cigarette users who chose to use the menthol e-cigs had greater use and satisfaction than those who chose other flavors. These preliminary findings suggest that dose and flavor influence e-cig use and satisfaction, but these findings will need to be confirmed using the full sample. Results from the full sample will potentially help inform the FDA's impending regulations regarding e-cigs. This project was completed with contributions from Jason Robinson from the M.D. Anderson Cancer Center.en-USThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).Poster