Multi-spectral Laser Scanning Confocal Microscopy with Structured Illumination

dc.contributor.advisorLe, Han Q.
dc.contributor.committeeMemberPei, Shin-Shem Steven
dc.contributor.committeeMemberWolfe, John C.
dc.contributor.committeeMemberWood, Lowell T.
dc.contributor.committeeMemberDonnelly, Vincent M.
dc.creatorShi, Tuo
dc.date.accessioned2019-09-09T17:09:44Z
dc.date.available2019-09-09T17:09:44Z
dc.date.createdMay 2016
dc.date.issued2016-05
dc.date.submittedMay 2016
dc.date.updated2019-09-09T17:09:50Z
dc.description.abstractThere is a need for high-resolution laser imaging system for health/life science and industrial applications, especially for microelectronics wafer inspection with increasingly shrinking feature size and nano materials characterization. A variety of super resolution methods have been invented in the last two decades to overcome the light diffraction limit barrier (so called Abbe’s theory), such as structured illumination microscopy (SIM) and related techniques. This dissertation introduces a novel method of combining SIM and laser scanning confocal microscopy, which is widely used in industrial metrology inspection and health/life science. This technique is multi-spectral-scalable, and provides a dye-free solution to bypass Abbe’s resolution barrier and can be easily implemented in most of the existing confocal microscopes. The theoretical concept, numerical simulations, structured illumination imaging results, and multi-spectral imaging results are presented in this dissertation.
dc.description.departmentElectrical and Computer Engineering, Department of
dc.format.digitalOriginborn digital
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/10657/4376
dc.language.isoeng
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.subjectConfocal microscopy
dc.subjectStructured Illumination Microscopy
dc.subjectMulti-spectral
dc.subjectLaser scanning
dc.subjectSuper Resolution imaging
dc.subjectCDMA
dc.subjectFDTD
dc.subjectSimulations
dc.titleMulti-spectral Laser Scanning Confocal Microscopy with Structured Illumination
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCullen College of Engineering
thesis.degree.departmentElectrical and Computer Engineering, Department of
thesis.degree.disciplineElectrical Engineering
thesis.degree.grantorUniversity of Houston
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy

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