Steroselective total syntheses of diterpene resin acids

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dc.contributor.advisorWelch, Steven C.
dc.contributor.committeeMemberThummel, Randolph Paul
dc.contributor.committeeMemberKohn, Harold Lewis
dc.contributor.committeeMemberZlatkis, Albert
dc.creatorKim, Jung Han
dc.date.accessioned2022-02-14T19:34:52Z
dc.date.available2022-02-14T19:34:52Z
dc.date.issued1976
dc.description.abstractA stereoselective total synthesis of ([plus-minus])-callitrisic acid (1) from p-isopropenyliospropylbenzene via intermediate keto-ester 59, as well as a stereoselective total synthesis of ([plus-minus])-podocarpic acid (.2) from enone 63 via intermediate keto-ester 64 are described. The synthetic approach involves a new and highly stereoselective reductive-elimination-alkylation reaction on vinyl ether esters 61 and 65, respectively. Lithium in liquid-ammonia followed by methyl iodide was used for the simultaneous reduction, deoxygenation, and stereoselective alkylation in single step.
dc.description.departmentChemistry, Department of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other3454959
dc.identifier.urihttps://hdl.handle.net/10657/8803
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. §107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.titleSteroselective total syntheses of diterpene resin acids
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Natural Sciences and Mathematics
thesis.degree.departmentChemistry, Department of
thesis.degree.disciplineChemistry
thesis.degree.grantorUniversity of Houston
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy

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