Induction of HFR formation in F[raised +] males of Escherichia coli treated with MNNG

dc.contributor.committeeMemberGoldschmidt, Eugene P.
dc.contributor.committeeMemberEvans, John E.
dc.contributor.committeeMemberKimball, Aubrey P.
dc.contributor.committeeMemberAumann, Glenn David
dc.creatorPledger, Warren Jackson
dc.description.abstractN-methyl-N'-nitro-N-nitrosoguanidine, MNNG, was shown to stimulate the formation of Hfr males in a F[raised +] population of Escherichia coli. The frequency of Hfrs is raised 23.3 fold, with MNNG treatment, above that of spontaneous Hfr formation. At least twelve different sites of F factor integration were found in MNNG induced Hfrs. Several possible mechanisms of the MNNG induced F factor integration process were studied. A model for Hfr formation has been discussed.
dc.description.departmentBiology and Biochemistry, Department of
dc.format.digitalOriginreformatted digital
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dc.titleInduction of HFR formation in F[raised +] males of Escherichia coli treated with MNNG
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