Studies on the metabolism of dimethisterone and norethisterone in the human

Steroidal drug metabolites isolated from human urinary extracts after oral administration of dimethisterone (6[alpha]-methyl-17[alpha]- (1-propynyl)-17[beta]-hydroxyandrost-4-en-3-one) and norethisterone (17[alpha]-ethynyl-17[beta]hydroxyestr-4-en-3-one) were identified by gas chromatography and combined gas chromatography-mass spectrometry. [...]