Interfacial tension effects of nonionic surfactants in reversed-phase high performance liquid chromatography

dc.contributor.advisorDeming, Stanley N.
dc.contributor.committeeMemberClifford, Dennis A.
dc.contributor.committeeMemberWendlandt, Wesley W.
dc.contributor.committeeMemberGeanangel, Russell A.
dc.contributor.committeeMemberLeggett, David J.
dc.creatorTang, Muoi
dc.date.accessioned2023-12-07T16:12:27Z
dc.date.available2023-12-07T16:12:27Z
dc.date.issued1982
dc.description.abstractA quantitative thermodynamic model is derived to describe the retention behavior of an injected solute as a function of an added amphipathic modifier in the eluent of a reversed-phase liquid chromatographic system. In this model, the addition of surfactant to the eluent can influence the retention time of the chromatographic solute in two ways: by decreasing the interfacial tension; and, for charged surfactants, through electrostatic interactions between the charged solute and the charged surfactant in the adsorbed phase. The retention phenomena of zwitterionic, negatively charged, and positively charged compounds on a C18 column was studied using aqueous solutions containing different concentrations of nonionic and partially ionized surfactants. The results of this study indicate that addition of surfactant to the eluent reduces the interfacial tension and thus decreases the retention time of the injected solutes. When the surfactant is partially charged, there are additional strong interactions between the surfactant and charged injected solutes in the adsorbed phase. When the surfactant is uncharged, there is almost no interaction between the surfactant and charged and uncharged injected solutes in the adsorbed phase.
dc.description.departmentChemistry, Department of
dc.format.digitalOriginreformatted digital
dc.format.mimetypeapplication/pdf
dc.identifier.other9107191
dc.identifier.urihttps://hdl.handle.net/10657/15551
dc.language.isoen
dc.rightsThis item is protected by copyright but is made available here under a claim of fair use (17 U.S.C. Section 107) for non-profit research and educational purposes. Users of this work assume the responsibility for determining copyright status prior to reusing, publishing, or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions requires express permission of the copyright holder.
dc.subjectLiquid chromatography
dc.subjectSurface chemistry
dc.titleInterfacial tension effects of nonionic surfactants in reversed-phase high performance liquid chromatography
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Natural Sciences and Mathematics
thesis.degree.departmentChemistry, Department of
thesis.degree.disciplineChemistry
thesis.degree.grantorUniversity of Houston
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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