Comparative Effectiveness of Smoking Cessation Medications among Obese Smokers

dc.contributor.advisorAbughosh, Susan M.
dc.contributor.committeeMemberChen, Hua
dc.contributor.committeeMemberJohnson, Michael L.
dc.contributor.committeeMemberEssien, Ekere James
dc.contributor.committeeMemberPeters, Ronald J.
dc.creatorYang, Mo 1985-
dc.date.accessioned2015-08-25T01:40:11Z
dc.date.available2015-08-25T01:40:11Z
dc.date.createdAugust 2013
dc.date.issued2013-08
dc.date.updated2015-08-25T01:40:11Z
dc.description.abstractObjective I: To compare the continuous abstinence rates of FDA-approved smoking cessation medication strategies during a) 3 months, b) 6 months, and b) 12 months follow up period among obese smokers. Hypothesis (Ha): Abstinence rates among obese smokers using varenicline will be higher compared to obese smokers using bupropion during a)3, b)6, and c)12 month follow-up after treatment initiation. Objective II: To compare the post-cessation weight gain between the two FDA-approved smoking cessation medications during: a) 3 months, b) 6 months, and c) 12 months of follow up period. Hypothesis (Ha): Obese smokers using bupropion experience lesser weight gain compared to those obese smokers using varenicline during a)3, b)6, and c)12 month follow-up after treatment initiation. Objective III: To compare the risk of developing diabetes following smoking cessation during the first year follow up among obese smokers between the FDA-approved smoking cessation medications (bupropion and varenicline). Hypothesis (Ha): Obese smokers using bupropion are less likely to develop diabetes following smoking cessation during a 1-year follow up compared to those using varenicline.
dc.description.departmentPharmacy, College of
dc.format.digitalOriginborn digital
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10657/1070
dc.language.isoeng
dc.rightsThe author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).
dc.subjectComparative effectiveness
dc.subjectSmoking cessation
dc.subjectAbstinence rate
dc.subjectObesity
dc.subjectWeight Change
dc.subjectType 2 Diabetes
dc.subjectVarenicline
dc.subjectBupropion
dc.subject.lcshPharmacy management
dc.titleComparative Effectiveness of Smoking Cessation Medications among Obese Smokers
dc.type.dcmiText
dc.type.genreThesis
thesis.degree.collegeCollege of Pharmacy
thesis.degree.departmentPharmacy, College of
thesis.degree.disciplinePharmacy Administration
thesis.degree.grantorUniversity of Houston
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy

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