Prevalence and correlates of anticipatory nausea and vomiting in children receiving chemotheraphy



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One of the most common and distressing side effects of chemotherapy treatment for cancer is severe nausea and vomiting which typically follows administration of chemotherapeutic agents with high emetogenic potential. After one or more courses of chemotherapy, patients may also develop nausea/vomiting responses prior to receiving chemotherapy. The prevalence and correlates of anticipatory nausea and/or vomiting (ANV) among pediatric patients has not been widely studied nor has previous research determined the extent of treatment team members' knowledge of the prevalence of ANV and severity of post-chemotherapy nausea/vomiting (PCNV) among their patients. Eighty-five pediatric patients who had received chemotherapy during the previous three months, their parents, amd members of their treatment team were surveyed to determine the prevalence of ANV and the severity of PCNV among these patients. Forty- four (52%) of the 85 patients/parents surveyed returned completed questionnaires. Each of the 3 physicians, 3 nurse practitioners, and 4 clinic nurses surveyed completed questionnaires, while 4 (22%) of the 18 hospital nurses completed them. Forty-six (54%) patients reported or were reported to have experienced ANV. There were significant differences among the rater groups in the proportion of patients reported to have experienced ANV. Patients/parents, clinic nurses, and hospital nurses reported a higher prevalence of ANV than either physicians or nurse practitioners. [...]



Cancer--Chemotherapy--Complications, Vomiting, Tumors in children