Bacillus safensis FO-36b and Bacillus pumilusSAFR-032: a whole genome comparison of two spacecraft assembly facility isolates

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Fox_2018_BacillusSafensisFO-36bandBacillusPumilus.pdf (3.76 MB)

Date

6/8/2018

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Publisher

BMC Microbiology

Abstract

Bacillus strains producing highly resistant spores have been isolated from cleanrooms and space craft assembly facilities. Organisms that can survive such conditions merit planetary protection concern and if that resistance can be transferred to other organisms, a health concern too. To further efforts to understand these resistances, the complete genome of Bacillus safensis strain FO-36b, which produces spores resistant to peroxide and radiation was determined. The genome was compared to the complete genome of B. pumilus SAFR-032, and the draft genomes of B. safensis JPL-MERTA-8-2 and the type strain B. pumilusATCC7061T. Additional comparisons were made to 61 draft genomes that have been mostly identified as strains of B. pumilus or B. safensis.

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Keywords

Planetary protection, Bacillus endospores, Extreme radiation resistance, Peroxide resistance, Genome comparison, Phage insertions

Citation

Copyright 2018 BMC Microbiology. Recommended citation: Tirumalai, Madhan R., Victor G. Stepanov, Andrea Wünsche, Saied Montazari, Racquel O. Gonzalez, Kasturi Venkateswaran, and George E. Fox. "Bacillus safensis FO-36b and Bacillus pumilus SAFR-032: a whole genome comparison of two spacecraft assembly facility isolates." BMC microbiology 18, no. 1 (2018): 57. DOI: 10.1186/s12866-018-1191-y. URL: https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-018-1191-y. Reproduced in accordance with the original publisher's licensing terms and with permission from the author(s).

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https://hdl.handle.net/10657/4231

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