State Dependent Effects of Transcranial Rotating Permanent Magnet Stimulation of the Primary Motor Cortex

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2017-10-12

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Non-invasive devices that stimulate the brain can enhance or suppress neuronal activity depending on the frequency, rate, and duration of stimuli. These devices can be useful in brain research, and may help diagnose and treat neuropsychiatric diseases in the future. For example, previous studies have shown that non-invasive brain stimulation alters the activity of cortical neurons. Stimulation of the primary motor cortex (PMC) activates muscles on the opposite side of the body because motor neurons within it control contralateral voluntary movements. Our aim was to study the effects on cerebral cortical and peripheral muscle activities produced by short continuous oscillatory stimuli delivered by the TRPMS device to a target PMC site. At the end of our study we found that there were state dependent increases in muscle response after the stimulation of the corresponding cortex. This project was completed with constributions from Santosh Helekar from the Houston Methodist Research Institute.

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