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    • Probing the Integrin Allostery by Thermal Stability and Affinity 

      Le, Trevor; Manandhar, Pragya (2017)
      αXβ2 integrin is central to the migration of myeloid cells during inflammatory response. The ligand binding domain of αXβ2, called αX I-domain, has a Mg2+-binding site (MIDAS) and an allosteric α7-helix. It has been ...