Now showing items 1-3 of 3

    • Aptamer-Phage Reporters for Ultrasensitive Lateral Flow Assays 

      Adhikari, Meena; Strych, Ulrich; Kim, Jinsu; Goux, Heather J.; Dhamane, Sagar; Poongavanam, Mohan-Vivekanandan; Hagstrom, Anna E. V.; Kourentzi, Katerina D.; Conrad, Jacinta C.; Willson, Richard C. (Analytical Chemistry, 2016-12)
      We introduce the modification of bacteriophage particles with aptamers for use as bioanalytical reporters, and demonstrate the use of these particles in ultrasensitive lateral flow assays. M13 phage displaying an in vivo ...
    • Detection of Viruses By Counting Single Fluorescent Genetically Biotinylated Reporter Immunophage Using a Lateral Flow Assay 

      Kim, Jinsu; Adhikari, Meena; Dhamane, Sagar; Hagstrom, Anna E. V.; Kourentzi, Katerina D.; Strych, Ulrich; Willson, Richard C.; Conrad, Jacinta C. (ACS Appl Mater Interfaces, 2016-02)
      We demonstrated a lateral flow immunoassay (LFA) for detection of viruses using fluorescently labeled M13 bacteriophage as reporters and single-reporter counting as the readout. AviTag-biotinylated M13 phage were functionalized ...
    • Sensitive Detection of Norovirus Using Phage Nanoparticle Reporters in Lateral-Flow Assay 

      Hagstrom, Anna E. V.; Garvey, Gavin; Paterson, Andrew S.; Dhamane, Sagar; Adhikari, Meena; Estes, Mary K.; Strych, Ulrich; Kourentzi, Katerina D.; Atmar, Robert L.; Willson, Richard C. (PLoS ONE, 2015-05)
      Noroviruses are recognized worldwide as the principal cause of acute, non-bacterial gastroenteritis, resulting in 19-21 million cases of disease every year in the United States. Noroviruses have a very low infectious dose, ...