Browsing Published ETD Collection by Issue Date
Now showing items 1-20 of 4218
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The mechanisms of chronic nadolol treatment on the regulation of bronchial tone in a murine model of asthma
(2008-08)Statement of the problem: Using a murine model of asthma, chronic beta blocker treatment was found to improve airway hyperresponsiveness (AHR). This finding completed a paradigm shift in the treatment of asthma using ... -
Impacts of Size on Pharmacokinetics and Biodistributions of Mebendazole Nanoformulations in Mice and Rats
(2008-08)Mebendazole (Mbz), a poorly water-soluble anthelminthic drug, possesses siginificant antineoplastic effects in both in vitro and in vivo studies. Microemulsions (PM1 37nm and PM2 478 nm) and nanosuspensions (NS-167nm, ... -
Correspondence of directly and indirectly measured built environment attributes and physical activity adoption among African American and Hispanic or Latina Women
(2010-05)Ethnic minority women report poorer health outcomes and attitudes and are more vulnerable to overweight and/or obesity compared to Caucasian women. Epidemiological studies and ecologic models of health behavior suggest ... -
Relationship Between Flavonoid Structure And Phase-II Metabolism
(2010-05)Objective: The overall objective is to develop structure-metabolism relationships (SMRs) between UGTs and flavonoids for predicting glucuronidation of flavonoids. The goals of this research project were to: 1) identify the ... -
Exploring a Broader View of Technology Acceptance
(2010-05)The primary aim of this dissertation is to establish the generalizability of the scale items used to measure 5 psychological acceptance constructs proposed by Schwarz and Chin (2007). While an initial test of validity and ... -
Mechanisms of Exercise-Mediated Restoration of Renal Dopamine D1 Receptor Function in Aging
(2010-05)Renal dopamine plays a pivotal role in the maintenance of sodium homeostasis and blood pressure. Dopamine by activating D1 receptors (D1R) and inhibiting sodium transporters, Na, K-ATPase and Na, H exchanger, in renal ... -
Gender difference affects absorption and disposition of soy isoflavones in rats
(2010-05)Female Sprague-Dawley rats showed 2-fold higher total oral bioavailability (14C genistein) than male rats. Due to experimental limitations of measurement of radioactivity count, the absolute oral bioavailability of genistein ... -
Motivational beliefs, ethnic identity, and sense of belonging: Relations to school engagement and academic achievement
(2010-05)Students’ motivational beliefs, sense of belonging, and ethnic identity were examined in relation to effort, persistence, procrastination, school attendance, and academic achievement. A total of 589 seventh and eighth ... -
CHRONIC STRESS REVEALS COGNITIVE IMPAIRMENT IN A SUBTHRESHOLD AMYLOID-BETA MODEL OF ALZHEIMER’S DISEASE
(2010-05)Although it is generally accepted that Aβ contributes to the pathogenesis of Alzheimer's disease (AD), other factors that impact the severity and time of onset of the disease are not well known. Aside from genetic factors, ... -
THE PROTECTIVE EFFECTS OF CHRONIC CAFFEINE TREATMENT ON THE COGNITIVE FUNCTION AND SYNAPTIC PLASTICITY IN ACUTE SLEEP DEPRIVATION
(2010-05)Study objectives: Accumulating evidence has shown that caffeine and sleep deprivation have opposing effects on learning and memory; therefore, this study was undertaken to provide a detailed account of the effect of chronic, ... -
Binding and Signaling Differences between Prostaglandin E1 and E2 Mediated by Prostaglandin E Subtype Receptors
(2010-08)Prostaglandin E1 (PGE1) and E2 (PGE2) are ligands for the prostaglandin E2 receptor (EP) family, which consists of four subtype receptors, designated as EP1, EP2, EP3 and EP4. Interestingly, PGE2 mediates inflammation ... -
Factors that infuence age of identification of children with autism and pervasive developmental disorder nos
(2010-08)Early diagnosis of autism spectrum disorders (ASD) is crucial because early identification can lead to early intervention, which has been shown to improve the outcome of children diagnosed with ASD. This study explored ... -
Self-perceived and actual knowledge of Attention-Deficit Hyperactivity/Disorder: A comparison between graduate students in medicine,mental health, and education
(2010-08)Attention-Deficit/Hyperactivity Disorder (ADHD) is a common and increasingly diagnosed disorder among school-age children. Medical professionals, mental health professionals and educators can play an integral role in the ... -
Interpreting The Process Of Configuration of Packaged Software Through the Lens of Social Construction of Technology
(2010-08)Despite the predominance of packaged application software, information systems (IS) researchers have focused more on custom software development. Packaged software deserves to be investigated separately due to the uniqueness ... -
Understanding the Relationship of Multicultural Case Conceptualization, Multicultural Counseling Self-Efficacy, and Ethnocultural Empathy in Psychology Trainees
(2010-08)The multicultural competency instruments have been criticized for their ability to accurately assess this construct. Specifically, the lack of adherence to an operationalized definition is at the heart of the problem. In ... -
Factor Structure and Validity of the Lesbian, Gay, and Bisexual Knowledge and Attitude Scale for Heterosexuals (LGB-KASH)
(2010-08)Heterosexual attitudes toward Lesbian, Gay, and Bisexual (LGB) individuals have become the focus of recent research as sexual minorities and allies have advocated for LGB human rights issues and have subsequently captured ... -
Perfectionism, Societal Messages, Gender and Race as Correlates of Male Body Image
(2010-08)Many men experience psychological distress as they try to obtain the ideal body as constructed by society (Pope, Phillips, and Olivardia, 2000). The number of articles focusing on men and muscularity has greatly increased ... -
MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA
(2010-08)Purpose: Clinically, keratoconus is a condition associated with corneal ectasia, thinning, steepening and scarring, and sometimes necessitates transplant surgery. Exactly where this corneal pathology starts, what structures ... -
Neuronal and Mitochondrial Protection in Chronic Parkinsonism
(2010-08)Among the several plausible neuropathological hypotheses underlying the progression of aging and neurodegenerative diseases such as Parkinson’s disease (PD), oxidative stress and mitochondrial damage have emerged as one ... -
Voices of Assistant Principals on the Importance of Student Discipline to Effective Schools
(2010-12)Research in education, criminology, and sociology has long suggested that there is a strong, reciprocal connection between students’ behaviors in school and their academic achievement. Student misbehavior in schools has ...