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A Free Heme Perspective to Sickle Hemoglobin Polymerization
Sickle cell hemoglobin (HbS) polymerization is considered to be the primary pathogenic event in the sickle cell anemia. Many cellular and molecular factors have been identified so far as contributor towards the polymerization ...
A MICROFLUIDICS APPROACH TOWARDS THE INVESTIGATION OF FREE HEME EFFECTS ON SICKLE CELL HEMOGLOBIN POLYMERIZATION
Sickle cell hemoglobin (HbS) polymerization is considered to be the primary pathogenic event in sickle cell anemia. In this work we aim at fabricating an integrated microfluidic device with a localized microheater for the ...