Browsing by Department "Biomedical Engineering, Department of"
Now showing items 1-20 of 91
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A Heart Artificial: Building the Foundation for the Development and Maintenance of In Vitro Tissue Mimetic Cardiovascular Models
(2015-05)Given the prevalence of cardiovascular disorders and the distinct lack of significant repair mechanisms within cardiovascular systems, effective therapy for long-term treatment of cardiovascular degeneration remains a ... -
A Low Cost Wireless Sensor Interface for the Quantification of Tremor in Parkinson’s Disease
(August 201)Deep brain stimulation surgery involves placing an electrode in the deep brain to suppress the motor symptoms of patients with Parkinson’s disease (PD). Currently physicians use the standard Unified Parkinson’s Disease ... -
Ablation of Retbindin, the Riboflavin Binding Protein, Exacerbates Retinal Degenerative Phenotypes in Mouse Models of Human Retinal Diseases
(2020-05)Retbindin (Rtbdn) is a retina-specific, riboflavin binding protein, expressed only by the rod photoreceptor cells. Riboflavin is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which are ... -
Acoustic Detection of Coronary Artery Occlusions Before and After Stent Placement Using an Electronic Stethoscope
(2014-08)More than 380,000 Americans die every year from coronary artery disease (CAD). Early detection and treatment are crucial to reducing this number. Current diagnostic methods are invasive, costly, and time-consuming. Using ... -
Analysis of the Spatio-Temporal Dynamics of Infection
(2017)Spatio-temporal dynamics are vital in understanding the course of infection, particularly for infections that lead to the formation of granulomas such as Mycobacterium tuberculosis which significantly impact the course of ... -
Assessing Mouse Brain Elasticity Using Air-Pulse Based Optical Coherence Elastography
(2017)Current diagnostic methods are able to detect severe brain trauma but are unable to detect the microscopic brain injuries that regularly occur during a concussion. Our research aims to explore a potential alternative method ... -
Assessing Teratogen-Induced Changes in Murine Fetal Brain Vasculature Using In Utero Optical Coherence Tomography
(2020-05)This dissertation reports the use of in utero optical coherence tomography to evaluate changes in vasculature in a developing murine fetal brain caused due to prenatal exposure to teratogens. Embryogenesis is a highly ... -
Assessing the Vasculature Changes in Murine Fetal Brain Upon Alcohol Exposure
(2017)Fetal Alcohol spectrum disorder (FASD) refers to a broad spectrum of abnormalities that arise due to prenatal alcohol exposure (PAE). The severity of the abnormality depends on the amount of alcohol consumed and period of ... -
Assessing Tissue Biomechanical Properties with Noncontact Dynamic Optical Coherence Elastography
(May 2018)This dissertation reports the development of noncontact techniques to quantify the biomechanical properties of various tissues utilizing optical coherence elastography. These techniques are critical for screening, detection, ... -
Assessment of Mental Workload by EEG+fNIRS
(2017-05)Due to the high cognitive demands of modern technology on operators, recent studies have focused on quantitative assessment of mental workload (MWL) in order to enhance the performance, safety, and productivity in working ... -
Bedside Washing of Stored Red Blood Cells: A Simple Apparatus Based on Microscale Sedimentation in Normal Gravity
(2015-05)The aim of this study was to develop and evaluate a simple, inexpensive bedside RBC washer with the capability to process multiple pRBC units within a short period without any alteration to current blood collection and ... -
Bioengineering A Three-Dimensional Cardiac Left Ventricle
(2015-05)Hypoplastic left heart syndrome (HLHS) is a congenital condition characterized by an underdeveloped left ventricle (LV). The current treatment options are surgery and/or heart transplant. Current tissue engineering ... -
Biomechanical Effects of Custom Corneal Cross-Linking Using Optical Coherence Elastography
(2018)Keratoconus is a progressive disease of the eye which causes the cornea to become weak and thin. If untreated, it may lead to corneal deformation and impaired vision. Corneal collagen cross-linking (CXL) is a recently ... -
Biomechanics and Electromyography Inassessing Female Stress Urinary Incontinence
(2016-12)Introduction: Stress urinary incontinence (SUI), the involuntary urinary leakage associated with increases in intra-abdominal pressure, has a prevalence of 25–50% in U.S. women and the number of those who will undergo ... -
CARBON MONOXIDE ADSORPTION ON Pt MONOLAYER ON Pd(hkl) SURFACE STUDIED BY SUBTRACTIVELY NORMALIZED INTERFACIAL FOURIER TRANSFORM INFRA-RED SPECTROSCOPY
(2012-08)The progress of our civilization is critically dependent on the discovery of new materials and structures with better properties, novel functionality and applications. The ultra thin metal overlayers represent one class ... -
Coaxial Electrospinning of Protein-Encapsulated Core-Shell Nanofibers: Process Optimization and Release Modeling
(2019-12)Coaxial electrospinning is a novel method for encapsulation of protein drugs into polymeric materials for use in drug delivery systems. In this study, coaxial electrospinning was used to fabricate aligned polyethylene ... -
Correlation Analysis of Reward Modulation in Motor Cortex of Nonhuman Primates
(August 201)Reward modulation is represented in the motor cortex and can be used to implement more accurate decoding models to improve brain machine interfaces. Analyzing the trial-to-trial noise correlations between units in the ... -
Cortical Habituation of Acoustic Startle Reflex
(May 2015)The study of acoustic startle reflexes (ASR) has recently shown promising potential in augmenting the recovery of voluntary movement in patients who undergo neuro-rehabilitation. However, these ASRs have been associated ... -
Cortical Reorganization Characterization Using Multimodal EEG − FNIRS Integration Analysis
(2020-05)Introduction: Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) stand as state-of-the-art techniques for non-invasive functional neuroimaging. On a unimodal basis, EEG suffers from poor spatial ...