Browsing by Department "Biomedical Engineering, Department of"
Now showing items 1-20 of 47
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A Heart Artificial: Building the Foundation for the Development and Maintenance of In Vitro Tissue Mimetic Cardiovascular Models
(2015-05)Given the prevalence of cardiovascular disorders and the distinct lack of significant repair mechanisms within cardiovascular systems, effective therapy for long-term treatment of cardiovascular degeneration remains a ... -
A Low Cost Wireless Sensor Interface for the Quantification of Tremor in Parkinson’s Disease
(2016-08-16)Deep brain stimulation surgery involves placing an electrode in the deep brain to suppress the motor symptoms of patients with Parkinson’s disease (PD). Currently physicians use the standard Unified Parkinson’s Disease ... -
Acoustic Detection of Coronary Artery Occlusions Before and After Stent Placement Using an Electronic Stethoscope
(2014-08)More than 380,000 Americans die every year from coronary artery disease (CAD). Early detection and treatment are crucial to reducing this number. Current diagnostic methods are invasive, costly, and time-consuming. Using ... -
Analysis of the Spatio-Temporal Dynamics of Infection
(2017)Spatio-temporal dynamics are vital in understanding the course of infection, particularly for infections that lead to the formation of granulomas such as Mycobacterium tuberculosis which significantly impact the course of ... -
Assessing Mouse Brain Elasticity Using Air-Pulse Based Optical Coherence Elastography
(2017)Current diagnostic methods are able to detect severe brain trauma but are unable to detect the microscopic brain injuries that regularly occur during a concussion. Our research aims to explore a potential alternative method ... -
Assessing the Vasculature Changes in Murine Fetal Brain Upon Alcohol Exposure
(2017)Fetal Alcohol spectrum disorder (FASD) refers to a broad spectrum of abnormalities that arise due to prenatal alcohol exposure (PAE). The severity of the abnormality depends on the amount of alcohol consumed and period of ... -
Assessing Tissue Biomechanical Properties with Noncontact Dynamic Optical Coherence Elastography
(2018-05-10)This dissertation reports the development of noncontact techniques to quantify the biomechanical properties of various tissues utilizing optical coherence elastography. These techniques are critical for screening, detection, ... -
Bioengineering A Three-Dimensional Cardiac Left Ventricle
(2015-05)Hypoplastic left heart syndrome (HLHS) is a congenital condition characterized by an underdeveloped left ventricle (LV). The current treatment options are surgery and/or heart transplant. Current tissue engineering ... -
Biomechanical Effects of Custom Corneal Cross-Linking Using Optical Coherence Elastography
(2018)Keratoconus is a progressive disease of the eye which causes the cornea to become weak and thin. If untreated, it may lead to corneal deformation and impaired vision. Corneal collagen cross-linking (CXL) is a recently ... -
CARBON MONOXIDE ADSORPTION ON Pt MONOLAYER ON Pd(hkl) SURFACE STUDIED BY SUBTRACTIVELY NORMALIZED INTERFACIAL FOURIER TRANSFORM INFRA-RED SPECTROSCOPY
(2012-08)The progress of our civilization is critically dependent on the discovery of new materials and structures with better properties, novel functionality and applications. The ultra thin metal overlayers represent one class ... -
Cortical Habituation of Acoustic Startle Reflex
(May 2015)The study of acoustic startle reflexes (ASR) has recently shown promising potential in augmenting the recovery of voluntary movement in patients who undergo neuro-rehabilitation. However, these ASRs have been associated ... -
Deep Learning Enables High-Precision Classification of Morphology of Stored Red Blood Cells
(2018)About 15 million unit of stored red blood cells are transfused to nearly 5 million patients each year in the United States alone. However, the key properties of red blood cells progressively deteriorate during hypothermic ... -
Design and Fabrication of Ultra-Thin Soft Sensors Based on Electrospun Metal Oxide Semiconductors
(2018-05-10)The advancement of bioelectronics in the health care field has increased in recent years. To better their use, non-invasive continuous monitoring patch-sensors have been developed by increasing conformal mounting and ... -
Development of Real Time Sensing Systems to Assess the Electrophysiological Properties of Bioengineered Cardiac Tissues
(2015-05)Heart disease and heart failure are prevalent issues resulting in thousands of deaths every year. Unfortunately, current treatments do not present viable long-term solutions for heart disease; the only true solution to ... -
Discovery and Validation of IgG4 Anti-Gliadin Autoantibody as a Disease Marker of Psoriasis
(2018-05-10)Antigen microarray is a high-throughput technology, which can be used to select potential biomarkers. In this paper, antigen microarray is the main technology used to determine potential autoantibody biomarkers in different ... -
Distinguishing Colon Pathologies by Optical and Mechanical Contrast using Optical Coherence Elastography and Optical Coherence Tomography
(2018)Colon pathologies including colorectal cancer (CRC) and ulcerative colitis (UC) affect nearly 200,000 people per year. Early detection of these pathologies is crucial for positive prognoses. However, screening of CRC and ... -
Effect of High-Fat Diet on Systemic Lupus Erythematosus
(2017)Systemic lupus erythematosus (SLE) is chronic disease where normal tissues attacked by the body’s immune system. Discover how SLE and CVD positively impact one another as well as other influencing factors, such as lifestyle, ... -
Fabrication and Investigation of Conducting Polymer Micro and Nano Structures for Bioelectronics Applications
(2018-05-01)Conducting polymers (CPs), especially poly(3,4-ethylenedioxythiophthene) (PEDOT) and poly(pyrrole) (PPy), are ideal materials for bioelectronics devices because of their biocompatibility, mechanical properties that are ... -
Flavin Homeostasis in the Mouse Retina During Aging and Diabetes as a Marker for Retina Health
(2017)Nutritive and therapeutic intervention to restore the retina energy metabolism can lead to delayed onset and progression of blindness because of aging and type I and II diabetes.